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目的:分析某肿瘤医院药品不良反应(ADR)发生特点,促进临床合理用药。方法:采用描述性研究方法,对该院2008年325例报告进行分析。结果:325例ADR中,男188例,女137例,涉及怀疑药品128种,抗肿瘤药引发的ADR最多(169例次),累及的系统-器官以皮肤附件损害最多。新报告的ADR(31例)占总例数9.54%,其中中药注射液引发9例(29%)。医护人员报告ADR意识不强,部分科室报表数过少。结论:应完善ADR相关制度、加强医护人员的ADR宣传教育,提高ADR报告的数量与质量。
Objective: To analyze the characteristics of adverse drug reaction (ADR) in a tumor hospital and promote the rational use of clinical medicine. Methods: Using descriptive research methods, the hospital in 2008 325 cases were analyzed. Results: Of the 325 ADRs, 188 were male and 137 were female, involving 128 suspected drugs. The most ADR was caused by antitumor agents (169 cases), and the most affected systemic-organ damage was skin attachment. The newly reported ADR (31 cases) accounted for 9.54% of the total cases, of which 9 cases (29%) were induced by Chinese traditional medicine injection. Medical staff report ADR awareness is not strong, some departments report too few. Conclusion: The relevant system of ADR should be perfected, ADR publicity and education of medical staff should be strengthened, and the quantity and quality of ADR report should be improved.