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恶性淋巴瘤病人的疗效未完全确定,对何杰金氏病(HD)剖腹脾切效应的评价已不如过去那么高。非何杰金氏淋巴瘤(NHL)已不再常规进行剖腹术。本文报道6例平均年龄49岁,男女各3例,均有巨脾,无淋巴结肿大,其组织学诊断是通过切脾确定。6例中3例单纯脾肿大,其中1例伴有消瘦、发热等全身症状,另3例有全血细胞减少的有关症状,1例伴有严重的自身免疫性溶血性贫血。按分期,Ⅲ期1例,Ⅳ期5例,其中肝受累4例,有骨髓病变3例。无一例有肿大的淋巴结适合作活检,骨髓穿刺和活检也未作出最后结论。6例巨脾均有肿瘤病变(平均重量1645g),组织结构:4例为低分级NHL,其中1例有恶性组织细胞增多,1例为混合细胞型HD,另
The efficacy of patients with malignant lymphoma is not fully determined, the evaluation of the effect of laparotomy splenectomy on Hodgkin’s disease (HD) is not as high as in the past. Non-Hodgkin’s lymphoma (NHL) is no longer routine laparotomy. This article reports 6 cases, mean age 49 years old, 3 males and 3 females, all with splenomegaly, no lymphadenopathy, histological diagnosis is determined by splenectomy. Of the 6 patients, 3 had simple splenomegaly, of which 1 had systemic symptoms of emaciation and fever, the other 3 had pancytopenia-related symptoms and 1 had severe autoimmune hemolytic anemia. According to stage, stage Ⅲ in 1 case, stage Ⅳ in 5 cases, including liver involvement in 4 cases, with bone marrow lesions in 3 cases. No case of enlarged lymph nodes suitable for biopsy, bone marrow biopsy and did not make the final conclusion. Six cases of giant spleen tumor lesions (average weight 1645g), organizational structure: 4 cases of low-grade NHL, including 1 cases of malignant cells, 1 case of mixed cell type HD, and the other