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5q 缺失(5q~-)综合征的特点为:1.多见于老年女性,男与女之比率为0.5。诊断时中数年龄65岁,20岁以下的患者<50%。2.呈巨细胞性贫血,血小板数正常或增高。骨髓内红系低下,存在不分叶的巨核细胞。3.临床过程较轻,进展为急性白血病颇不经常。4.诊断时约2/3的患者骨髓内原始细胞<5%,为5q~-难治性贫血(5q-RA),其余1/3患者原始
5q deletion (5q ~ -) syndrome is characterized by: 1. Prevalent in older women, male to female ratio of 0.5. The median age at diagnosis is <50% of patients under 20 years of age. 2. Giant cell anemia, normal or increased platelet count. Bone marrow erythroid, there is not divided leaf megakaryocytes. 3. The clinical course of light, progress to acute leukemia is quite infrequent. 4. Approximately two-thirds of patients diagnosed with less than 5% of primary bone marrow cells were 5q-refractory anemia (5q-RA) and the remaining 1/3