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目的:分析高血压合并冠心病给予药物联合降压治疗的临床效果。方法:在我院于2013年6月至2014年6月期间收治的高血压合并冠心病患者中,抽选60例作为研究对象。使用氨氯地平、贝那普利联合治疗,观察患者的血压水平变化和不良事件发生情况。结果:患者治疗后显效49例、有效11例,治疗有效率达到100%;用药过程中出现心绞痛、心力衰竭、阵发性干咳共计7例(11.7%)。患者治疗2周、3个月、6个月后的收缩压、舒张压均持续降低,和治疗前相比差异有统计学意义(P<0.05)。结论:药物联合治疗高血压合并冠心病效果确切,使用氨氯地平、贝那普利能够实现平稳降压的目标,且不良事件发生少,值得临床推广。
Objective: To analyze the clinical effect of antihypertensive treatment of hypertension combined with coronary heart disease. Methods: Among the patients with hypertension complicated with coronary heart disease admitted in our hospital from June 2013 to June 2014, 60 patients were selected as the research object. Amlodipine, benazepril combined treatment, observation of patients with changes in blood pressure levels and adverse events. Results: After treatment, 49 cases were markedly effective and 11 cases were effective. The effective rate was 100%. Angina pectoris, heart failure and paroxysmal dry cough occurred in 7 cases (11.7%). The systolic blood pressure and diastolic blood pressure of patients after 2 weeks, 3 months and 6 months of treatment all continued to decrease, which was significantly different from that before treatment (P <0.05). Conclusion: The drug combination therapy of hypertension with coronary heart disease is effective. With amlodipine and benazepril, the goal of stable blood pressure reduction can be achieved with fewer adverse events, which is worthy of clinical promotion.