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我们应用“抗矽-14”(磷酸喹哌)对确诊的31例男性煤矽肺患者进行了疗效观察。31例的年龄为35～74岁,平均52岁,工龄10～55年,平均21年,Ⅰ期矽肺16例,Ⅱ期12例,Ⅲ期3例。每周服药一次,每次0.5克,睡前顿服。6个月为一疗程,共治疗二个疗程,疗程间隔1个月。治疗前和治疗后半年、一年均进行全面体检及血常规、肝功、生化、X 线胸片等检查。治疗结果认为,一般症状治疗后均有不同程度的改善,且病期越长,改善越明显。各主要症状好转和减轻的百分比为:Ⅰ期59%,Ⅱ期71%,Ⅲ期92%。尿羟脯氨酸、
We applied “anti-silicon-14” (quinpirine phosphate) in the diagnosis of 31 cases of male patients with coal silicosis were observed. The age of 31 cases was 35-74 years (mean 52 years). The length of service was 10-55 years with an average of 21 years. There were 16 cases of stage I silicosis, 12 cases of stage II and 3 cases of stage III. Medication once a week, each 0.5 grams, Dayton clothing before going to bed. 6 months for a course of treatment, a total of two courses of treatment, treatment interval of 1 month. Before treatment and after treatment for six months, a year to conduct a comprehensive physical examination and blood, liver function, biochemistry, X-ray examination. Treatment results suggest that the general symptoms have different degrees of improvement after treatment, and the longer the period, the more obvious improvement. The main symptoms of improvement and reduction in the percentage: Ⅰ 59%, Ⅱ 71%, Ⅲ 92%. Urine hydroxyproline,