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目的:探讨舌癌患者术后1年的生存质量变化及其相关影响因素。方法:选择2003-2005年中山大学附属第二医院口腔颌面外科手术治疗的93例舌癌患者,在术前及术后1年时,由患者自主完成华盛顿大学生存质量问卷(第4版)填写,分析生存质量的变化;利用SPSS11.5软件包进行非参数检验和多因素线性回归分析。结果:术后12个月,生存质量问卷的总体生存质量接近术前;术后12个月时,生存质量问卷的外形、行为、语言和肩部功能分值较术前显著下降,差异有统计学意义(P<0.05);而疼痛、抑郁和焦虑分值较术前升高,差异有统计学意义(P<0.05)。多因素回归分析显示,临床分期、放疗、年龄、社会经济因素影响生存质量。结论:早期发现、早期治疗舌癌,提高患者的社会经济水平,对提高生存质量有重要意义。
Objective: To investigate the changes of the quality of life of the patients with tongue cancer one year after operation and the related factors. METHODS: Ninety-three patients with tongue cancer undergoing oral and maxillofacial surgery in the Second Affiliated Hospital of Sun Yat-sen University from 2003 to 2005 were selected. The University of Washington’s QOL (Version 4) Fill in, analyze the change of quality of life; use SPSS11.5 software package for non-parametric test and multivariate linear regression analysis. Results: At 12 months after operation, the overall quality of life of the questionnaire for quality of life was close to preoperative. At 12 months after operation, the quality of life questionnaire’s appearance, behavior, language and shoulder function scores decreased significantly compared with that before operation, with statistical differences (P <0.05), while the scores of pain, depression and anxiety were significantly higher than those before surgery (P <0.05). Multivariate regression analysis showed that clinical stage, radiotherapy, age, socio-economic factors affect the quality of life. Conclusion: Early detection, early treatment of tongue cancer, improve the patient’s social and economic level, to improve the quality of life is of great significance.