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心钠素(ANF)是心脏分泌的一种循环激素,具有强大的利钠、利尿、扩血管作用。本文通过测定18例肝硬化腹水病人血浆ANF(P-ANF)水平,旨在探讨p-ANF在肝硬化腹水形成中的作用及意义。 1 临床资料患者组18例均系住院病人,男/女为13/5。年龄38~82岁。病程3~18a,平均8.2a。病因:肝炎后肝硬化11例、血吸虫性肝硬化4例、病因不明3例。除1例有不明原因蛋白尿外,均无心、肺、肾、内分泌疾病。其中少量腹水8例、中量5例、大量腹水5例。18例中11例无外周水肿,7例伴不同程度外周水肿。
Atrial natriuretic peptide (ANF) is a circulating hormone secreted by the heart, which has strong sodium, diuretic and vasodilator effects. In this paper, 18 cases of cirrhosis ascites plasma levels of ANF (P-ANF), aimed to explore the role of p-ANF in the formation of cirrhotic ascites and its significance. 1 Clinical data Patient group of 18 patients were in-patient, male / female 13/5. Age 38 ~ 82 years old. Course of disease 3 ~ 18a, an average of 8.2a. Etiology: hepatitis cirrhosis in 11 cases, 4 cases of schistosome cirrhosis, etiology in 3 cases. In addition to an unexplained proteinuria, no heart, lung, kidney, endocrine disease. A small amount of ascites in 8 cases, 5 cases in volume, a large number of ascites in 5 cases. Of the 18 patients, 11 had no peripheral edema and 7 had peripheral edema with varying degrees.