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目的:比较2型糖尿病患者血小板相关参数变化及临床意义。方法:测定52例2型糖尿病患者(糖尿病组)及健康体检者52例(对照组)血小板计数、血小板平均容积、血小板分布宽度、血小板压积,并进行比较。结果:糖尿病组血糖控制前、后血小板平均容积、血小板分布宽度、血小板压积均较对照组增高(P<0.01),血糖控制后血小板平均容积、血小板分布宽度、血小板压积较控制前降低(P<0.01);糖尿病组血糖控制前、后血小板计数与对照组比较差异均无统计学意义(P>0.05)。结论:检测2型糖尿病患者血小板相关参数的变化,对临床研究2型糖尿病及并发症的发生、发展有重要意义。
Objective: To compare the changes of platelet-related parameters in patients with type 2 diabetes mellitus and its clinical significance. Methods: The platelet count, average platelet volume, platelet distribution width and platelet pressure were measured in 52 patients with type 2 diabetes (diabetes mellitus) and 52 healthy people (control group), and compared. Results: Before and after blood glucose control, the average volume of platelets, the distribution width of platelets and the platelet pressure in the diabetic group were higher than those in the control group (P <0.01). The average volume of platelets, the distribution of platelets and the platelet pressure were decreased P <0.01). There was no significant difference in platelet count between before and after blood glucose control in diabetic group and control group (P> 0.05). Conclusion: Detecting the changes of platelet-related parameters in patients with type 2 diabetes mellitus is of great significance in the study of the occurrence and development of type 2 diabetes mellitus and complications.