论文部分内容阅读
[目的]观察步长脑心通联合西药治疗糖尿病周围神经病变疗效。[方法]使用随机平行对照方法,将94例门诊患者按就诊顺序号法简单随机分为两组。对照组47例低盐低脂、优质低蛋白饮食(蛋白摄入量<0.8g/kg·d-1),适当运动,降糖,控制空腹血糖<7.0mmol/L,餐后2h血糖<10mmol/L,保持血糖稳定;降压(β受体阻滞剂、血管紧张素II受体抑制剂、钙离子拮抗剂、利尿剂或血管紧张素酶转换抑制剂等)、降脂(他汀类、胆酸螯合剂等);甲钴胺1片/次,3次/d。治疗组47例步长脑心通1.2g/次,3次/d;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、MNCV、SNCV、不良反应。治疗6疗程,判定疗效。[结果]治疗组显效38例,有效7例,无效2例,总有效率95.74%。对照组显效27例,有效9例,无效11例,总有效率76.60%。治疗组疗效优于对照组(P<0.01)。MNCV神经传导速度两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。SNCV神经传导速度两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]步长脑心通联合西药治疗糖尿病周围神经病变疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Stephenxutong combined with western medicine on diabetic peripheral neuropathy. [Method] Using randomized parallel control method, 94 outpatients were randomly divided into two groups according to the sequence number of visiting doctor. In the control group, 47 cases of low-salt, low-fat, high-quality and low-protein diet with protein intake of <0.8g / kg · d-1 were given appropriate exercise and hypoglycemic to control fasting blood glucose <7.0mmol / L and postprandial blood glucose < / L, to maintain stable blood glucose; antihypertensive (beta blockers, angiotensin II receptor inhibitors, calcium antagonists, diuretics or inhibitors of angiotensin conversion, etc.), lipid-lowering (statins, Bile acid chelator, etc.); mecobalamin 1 tablet / time, 3 times / d. In the treatment group, 47 patients with stepwise brain-heart-Tong 1.2g / time, 3 times / d; Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, MNCV, SNCV, adverse reactions. Treatment of 6 courses to determine the efficacy. [Result] In the treatment group, 38 cases were markedly effective, 7 effective and 2 ineffective, with a total effective rate of 95.74%. The control group markedly effective in 27 cases, effective in 9 cases, ineffective in 11 cases, the total effective rate was 76.60%. The treatment group than the control group (P <0.01). MNCV nerve conduction velocity was improved in both groups (P <0.01), the treatment group improved better than the control group (P <0.01). SNCV nerve conduction velocity was improved in both groups (P <0.01), the treatment group improved better than the control group (P <0.01). [Conclusion] Buchang Naoxintong combined with Western medicine in the treatment of diabetic peripheral neuropathy is satisfactory, no serious adverse reactions, it is worth promoting.