论文部分内容阅读
头孢美唑(Cefmetazole)钠是一种新的注射头霉素类抗生素,对β-内酰胺酶稳定。杀菌作用迅速,杀菌浓度接近MIC。头孢美唑系广谱抗生素,对需氧及厌氧革兰氏阳性及阴性细菌的作用与其他结构相近的β-内酰胺类如头孢西丁、头孢替坦相似。但是对不动杆菌属,绿脓杆菌,耐甲氧西林金葡菌,肠球菌,大肠杆菌及粘质沙雷氏菌属无效。头孢美唑在日本已广泛用于临床各年龄组的各种感染性疾病患者。作者采用随机非盲对照研究方法比较了头孢美唑和头孢西丁治疗呼吸系统感染的疗效和安全性。本研究共选择68例呼吸道感染的住院患者(包括肺炎,慢性支
Cefmetazole Sodium is a new injectable cephalomycin antibiotic that stabilizes beta-lactamase. Rapid bactericidal effect, bactericidal concentration close to the MIC. Cefmetazole broad-spectrum antibiotics, aerobic and anaerobic Gram-positive and negative bacteria and other structures similar to β-lactams, such as cefoxitin, cefotetan similar. But for Acinetobacter, Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, Enterococcus, Escherichia coli and Serratia marcescens invalid. Cefmetazole has been widely used in patients with various infectious diseases in all age groups in Japan. The authors compared the efficacy and safety of cefmetazole and cefoxitin in the treatment of respiratory infections using a randomized, non-blind, controlled study. A total of 68 patients with respiratory tract infections (including pneumonia and chronic bronchitis) were selected for this study