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为研究中药制剂儿泻暖脐膏抗腹泻机制,对其抗腹泻,胃肠功能、镇痛及抗炎的药理作用进行了实验研究。结果儿泻暖脐膏能显著抑制小白鼠蓖麻油性及番泻叶性腹泻;显著抑制小白鼠小肠推进运动及皮下注射新斯的明的小肠推进运动;显著促进小白鼠胃排空运动;显著增加大白鼠血清D-木糖含量。
In order to study the anti-diarrhea mechanism of the traditional Chinese medicine preparation diarrhea warming umbilical ointment, the anti-diarrhea, gastrointestinal function, analgesic and anti-inflammatory pharmacological effects were studied experimentally. The results of diarrhea warming umbilical cord can significantly inhibit the mice castor oily and senna diarrhea; significantly inhibited small intestine advancing movement of mice and subcutaneous injection of neostigmine small intestine advancing movement; significantly promoted gastric emptying in mice; significant Increase serum D-xylose content in rats.