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本文对21例成人型颗粒细胞瘤患者的预后及病理学特征进行了回顾性分析。病理切片HE、PAS染色,免疫组化测定及电镜观查。结果;腹水中见瘤细胞畜存活年限明显少于无瘤细胞者;电镜下见低分化的瘤细胞核浆比例高,形态大小差异大,核膜凹陷情深切迹。结果:影响颗粒细胞瘤预后的因素是:腹水中有无癌细胞、肿瘤细胞的异型性、核分裂相多少或有无Call-Exner小体。
This article retrospectively analyzed the prognosis and pathological features of 21 adult patients with granular cell tumor. Pathological sections HE, PAS staining, immunohistochemistry and electron microscopy. Results Ascites showed that the survival time of tumor cells was significantly less than that of tumor-free cells. The electron microscopy showed that the tumor cells with poorly differentiated tumors had high proportion of nuclear plasma and large differences in the size of the tumor cells. Results: The prognostic factors of granulosa cell tumor were as follows: presence or absence of cancer cells, atypia of tumor cells, number of mitotic cells or presence of Call-Exner bodies in ascites.