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目的探讨出血性脑卒中并脑心综合征临床特点、发病机制及诊治体会。方法对2006年3月至2009年6月收治的48例出血性脑卒中并脑心综合征患者的临床资料进行回顾性分析。结果出血性脑卒中并脑心综合征多在出血后3~7d发生,除脑出血的临床表现外均有心电图异常及心肌酶谱升高,治疗上应注意保护心肌。其发生率为48.98%,且与脑出血部位有关,由高到低依次为:蛛网膜下腔、基底节区、脑干、小脑及脑叶出血。合并脑心综合征者的病死率明显高于未合并脑心综合征者(20.8%vs4.0%,P<0.05)。结论出血性脑卒中并脑心综合征与出血的部位有关,临床上应重视心电图检查及心肌酶谱测定,治疗上要注意保护心肌。
Objective To investigate the clinical characteristics, pathogenesis, diagnosis and treatment of hemorrhagic stroke and brain-heart syndrome. Methods The clinical data of 48 patients with hemorrhagic stroke and brain-heart syndrome admitted from March 2006 to June 2009 were analyzed retrospectively. Results Hemorrhagic stroke and brain-heart syndrome mostly occurred 3 ~ 7 days after hemorrhage. Except for the clinical manifestations of cerebral hemorrhage, both ECG abnormalities and myocardial enzymes were elevated. The treatment should pay attention to protecting the myocardium. The incidence was 48.98%, and with the site of cerebral hemorrhage, descending order: subarachnoid space, basal ganglia, brainstem, cerebellum and lobar hemorrhage. The mortality rate of patients with brain-heart syndrome was significantly higher than those without brain-heart syndrome (20.8% vs 4.0%, P <0.05). Conclusions Hemorrhagic stroke and brain-heart syndrome are related to the site of hemorrhage. ECG should be taken seriously and the myocardial enzymes should be measured clinically. The treatment should pay attention to the protection of the myocardium.