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【目的】探讨冠心病(CHD)合并糖耐量减低(IGT)患者血小板参数与超敏 C 反应蛋白(hs-CRP)的相关性。【方法】选取本院收治的CHD合并 IGT患者49例作为 A 组,单纯 CHD患者52例作为 B组,同期入院体检正常者55例作为对照组(C组),入院后均检测 hs-CRP及血小板计数(PLT)、血小板压积(PCT)、血小板分布宽度(PDW)、平均血小板体积(MPV)、大血小板比率(P-LCR)5项血小板参数水平,并了解其相关性。【结果】A 组 hs-CRP、PCT、PDW、MPV、P-LCR 分别为(7.94±0.51)mg/L、(0.24±0.04)%、(22.86±3.05)%、(16.04±3.97)fl、(59.68±8.24)%均显著高于B,C组,PLT为(148.37±29.79)×109/L显著低于 B, C组,B组和C组之间相比较差异亦具有显著性(P <0.05)；Pearson相关分析显示hs-CRP与PLT呈负相关关系,与PCT、PDW、MPV、P-LCR呈正相关关系。【结论】CHD合并 IGT 患者血小板参数与 hs-CRP 具有显著相关性。“,”Obj ective]To investigate the correlation between platelet parameters and hyper-sensitive C-re-active protein (hs-CRP)in patients with coronary heart disease complicated by impaired glucose tolerance.[Methods]Forty-nine patients with coronary heart disease (CHD)complicated by impaired glucose tolerance (IGT)were selected as CHD with IGT group,52 patients with CHD alone were selected as the CHD group, and 5 5 normal cases were selected as the control group.After admission,the levels of hs-CRP and 5 platelet parameters (PLT,PCT,PDW,MPV and P-LCR)were detected to analyze the correlation.[Results]In the CHD with IGT group,hs-CRP,PCT,PDW,MPV and P-LCR were(7.94±0.51)mg/L,(0.24±0.04)%, (22.86±3.05)%,(16.04±3.97)fl and(59.68±8.24)%,respectively which were significantly higher than those in the CHD group and the control group.PLT(148.37±29.79)×109/L was significantly lower than in the CHD group and the control group,however,the differences between the CHD group and the control group were statistically significant (P <0.05);The correlation between platelet parameters and hs-CRP was ana-lyzed by Pearson correlation analysis.It was found that hs-CRP was negatively correlated with PLT and posi-tively correlated with PCT,PDW,MPV and P-LCR.[Conclusion]The platelet parameters of patients with CHD complicated by IGT are significantly correlated with hs-CRP.