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目的探讨高血压对老年2型糖尿病的影响及各靶器官的损害。方法 72例2型糖尿病合并高血压病人按血压轻、中、重度分为A、B、C3组,对照组D组为45例血压正常的2型糖尿病患者,对比分析两组的脑梗死、冠心病、糖尿病肾病及眼底病变的发生率。结果 4组患者脑梗死(P=0.03)、冠心病(P=0.02)、糖尿病肾病(P=0.003)及眼底病变(P=0.002)的发生率具有极显著的统计学差异。结论老年2型糖尿病患者合并高血压脑梗死、冠心病、糖尿病肾病及眼底病变风险增高,且其严重程度随血压的增高而加重。
Objective To investigate the effect of hypertension on type 2 diabetes mellitus and the damage of various target organs. Methods Seventy-two patients with type 2 diabetes mellitus with hypertension were divided into A, B, and C3 groups according to their blood pressure, 45 patients with normotensive type 2 diabetes mellitus were divided into two groups: control group Heart disease, diabetic nephropathy and the incidence of retinopathy. Results The incidences of cerebral infarction (P = 0.03), coronary heart disease (P = 0.02), diabetic nephropathy (P = 0.003) and fundus lesions (P = 0.002) were significantly different among the four groups. Conclusion The elderly type 2 diabetic patients with hypertension cerebral infarction, coronary heart disease, diabetic nephropathy and ocular fundus lesions increased risk, and its severity increased with the increase of blood pressure.