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目的:比较冠心病(CHD)并发与不并发糖尿病(DM)患者行经皮冠状动脉介入治疗(PCI)操作特点,分析CHD并发DM患者冠状动脉病变特点,探讨临床上DM对PCI可能的影响。方法:对2006年1月~2006年12月在天津市胸科医院依顺序进行的全部1 441例行PCI术并植入金属支架的患者进行回顾性分析,按是否伴有DM分为两组:DM组和非DM组。收集患者PCI治疗各项参数,包括病变类型、病变参数、植入支架参数等。应用SPSS10.0软件进行统计学检验,计数资料以表示,P<0.05为差异有统计学意义。结果:在1 441例行PCI的患者中,DM患者共计223人,占15.5%。DM组C型病变比例明显高于非DM组(38.3%vs.19.7%;P<0.05)。DM组PCI治疗中治疗病变个数、植入支架个数明显多于非DM组(1.42±0.62vs.1.28±0.51;1.63±0.84vs.1.47±0.69,P<0.05),而植入支架直径DM组明显小于非DM组[(3.00±0.42)mmvs.(3.06±0.43)mm,P<0.05]。其余PCI操作技术特点差异无统计学意义。结论:CHD并发DM行PCI术者病变较非DM者更重;CHD并发DM患者进行PCI治疗时需要处理更多病变、植入更多支架,且支架直径较小;CHD并发DM患者接受PCI治疗的比例与非并发DM的CHD患者相比更低。
OBJECTIVE: To compare the characteristics of percutaneous coronary intervention (PCI) in patients with and without coronary heart disease (CHD) complicated with and without diabetes mellitus (DM) and analyze the characteristics of coronary lesions in CHD patients with DM and to explore the possible effect of DM on PCI. Methods: A total of 1 441 patients who underwent PCI with metal stent in Tianjin Chest Hospital from January 2006 to December 2006 were analyzed retrospectively according to whether they had DM or not : DM group and non-DM group. The parameters of PCI treatment were collected, including the type of the lesion, the parameters of the lesion and the parameter of the stent. Application SPSS10.0 software for statistical tests, counting data to indicate that P <0.05 for the difference was statistically significant. Results: Of the 1 441 PCI patients, 223 were DM patients, accounting for 15.5%. The proportion of type C lesions in DM group was significantly higher than that in non-DM group (38.3% vs.19.7%; P <0.05). The number of lesions treated with PCI in DM group was significantly more than that in non-DM group (1.42 ± 0.62 vs 1.28 ± 0.51; 1.63 ± 0.84 vs 1.47 ± 0.69, P <0.05) DM group was significantly smaller than that of non-DM group [(3.00 ± 0.42) mm vs (3.06 ± 0.43) mm, P <0.05]. The remaining PCI operation technical characteristics of the difference was not statistically significant. Conclusions: The lesions of patients with CHD with DM undergoing PCI are more serious than those without DM. Patients with CHD complicated with DM require more lesions to be treated with more stents and smaller stent diameters. Patients with CHD complicated with DM receive PCI Is lower in CHD patients with non-concurrent DM.