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目的分析妊娠期亚临床甲状腺降低孕妇甲状腺激素剂量的调整时间和规律，以及实施早期护理干预对胎儿的影响。方法60例怀孕2个月内的患者，根据孕前是否发现甲状腺减低症分为早期干预组和对照组，每组各30例；早期干预组患者及时接受左旋甲状腺素片治疗，并接受早期护理干预调整剂量；对照组患者为早孕检查时发现甲状腺功能减退患者，在发现时开始接受甲状腺素的治疗。结果对照组不同孕月甲状腺激素用量显著高于干预组(<0.05)；干预组激素达标孕周显著早于对照组(<0.05)；干预组促甲状腺素达标孕周显著早于对照组(<0.05)；两组患者分娩后婴儿未发现异常，但对照组的剖宫产率显著高于早期干预组(<0.05)。结论妊娠早期应当尽快明确甲状腺功能，同时对患者甲状腺水平进行监测，并进行及时调整，实施早期护理干预，减少甲状腺功能减退所致的妊娠不良结局。“,”Objective To analyze the adjustment time and the rule of thyroid hormone dose in pregnant women with subclinical hypothyroidism,and to study the effect of early nursing intervention on the fetus.Methods 60 cases of pregnancy within 2 months of patients,according to their prepregnant whether thyroid reduced disease divided into the early intervention group and control group,each with 30 cases in each;early intervention patients receive timely levothyroxine treatment,and received early nursing intervention dose adjustment;in the control group,patients in early pregnancy check found in hypothyroid patients.At the time of discovery began receiving thyroxine treatment.Results Control group in different months of pregnancy thyroid hormone dosage was significantly higher than that in the intervention group ( <0.05);intervention in the hormone group standard gestational weeks significantly earlier than the control group ( <0.05);intervention group promoting thyroxine standard gestational weeks significantly earlier than the control group ( <0.05);delivery of two groups after the baby was not abnormal,but the control group the rate of cesarean section was significantly higher than that in the early intervention group ( <0.05).Conclusion Early pregnancy should be as soon as possible a clear thyroid function and monitoring of patients with thyroid levels at the same time,and timely adjustment and implementation of early nursing intervention,reduce hypothyroidism caused by adverse pregnancy outcomes.