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胺对中枢神经系统、肝脏和各种组织都有毒性,故常被认为是肝昏迷的主要原因。本文报告了使用左旋多巴治疗肝昏迷的效果。肝病患者血和尿中的胺量较高,而肝昏迷患者则更为显著。血氨和游离氨态氮的比例也有所增加。此外还可以看到苯丙氨酸和酪氨酸增加,这在肝昏迷患者尤为显著。为了了解肝病患者儿茶酚胺代谢的情况,测定了慢性肝炎19例、肝硬化12例尿中的多巴、多巴
Amines are toxic to the central nervous system, liver and various tissues and are often considered as the main cause of hepatic coma. This article reports the efficacy of levodopa in the treatment of hepatic coma. The amount of amines in the blood and urine of patients with liver disease is higher, while the patients with hepatic coma are more pronounced. Blood ammonia and free ammonia nitrogen ratio also increased. In addition, one can see an increase in phenylalanine and tyrosine, which is particularly pronounced in patients with hepatic coma. In order to understand the catecholamine metabolism in patients with liver disease, 19 cases of chronic hepatitis, 12 cases of cirrhosis of the urine of dopa, dopa