论文部分内容阅读
目的观察酮替芬联合沙丁胺醇治疗小儿哮喘的临床治疗效果。方法选取2013年5月—2015年3月在自贡市第一人民医院就诊的哮喘患儿85例,采用随机数字表法分为对照组40例和观察组45例。对照组患儿给予常规综合治疗,观察组患儿在对照组基础上给予酮替芬联合沙丁胺醇治疗。比较两组患儿临床疗效、临床症状消退时间以及不良反应发生情况。结果观察组患儿临床疗效优于对照组(u=2.412,P=0.015)。观察组患儿咳嗽、气促、喘憋及肺部啰音消退时间均短于对照组(P<0.05)。观察组患儿不良反应发生率低于对照组(P<0.05)。结论酮替芬联合采用沙丁胺醇治疗小儿哮喘的临床疗效确切,可及时有效地改善患儿临床症状。
Objective To observe the clinical efficacy of ketotifen combined with salbutamol in the treatment of pediatric asthma. Methods From May 2013 to March 2015, 85 children with asthma admitted to the First People’s Hospital of Zigong City were divided into control group (n = 40) and observation group (n = 45) by random number table. The control group of children given conventional comprehensive treatment, observation group children in the control group on the basis of given ketotifen combined with salbutamol treatment. The clinical curative effect, the clinical symptom subsided time and the adverse reaction were compared between the two groups. Results The clinical efficacy of observation group was better than that of control group (u = 2.412, P = 0.015). The observation group cough, shortness of breath, wheezing and pulmonary rales were shorter than the control group (P <0.05). The incidence of adverse reactions in observation group was lower than that in control group (P <0.05). Conclusion Ketotifen combined with salbutamol treatment of pediatric asthma clinical curative effect is exact and timely and effectively improve the clinical symptoms of children.