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目的：评价高压氧综合治疗持续性植物状态患者的疗效并探讨其作用机理。方法：自１９９４年３月至１９９５年３月一年间，在常规治疗的基础上，应用高压氧治疗持续性植物状态患者８例（病因为严重颅脑损伤４例、脑出血２例、脑梗塞１例、脑膜瘤术后１例，其中昏迷时间最长为２８１天，其次为１４１天）；治疗压力为０．２ＭＰａ，吸纯氧４０分钟×２次，中间吸空气１０分钟，每天治疗１次，１０次为１个疗程。治疗次数最短者２０次，最长者８６次。结果：本组８例患者经上述治疗后全部清醒恢复意识。结论：高压氧治疗对持续性植物状态患者有显著疗效。对治疗时间较长超过４０次者，宜分阶段进行，并应注意加强营养供给。
OBJECTIVE: To evaluate the efficacy of hyperbaric oxygen in patients with persistent vegetative state and to explore its mechanism. Methods: From March 1994 to March 1995, 8 patients with persistent vegetative state were treated with hyperbaric oxygen on the basis of conventional therapy (the cause was severe traumatic brain injury in 4 cases, cerebral hemorrhage in 2 cases, cerebral infarction 1 case, 1 case of meningioma after surgery, the longest coma 281 days, followed by 141 days); treatment pressure of 0.2MPa, suction pure oxygen for 40 minutes × 2 times, the middle air suction for 10 minutes daily treatment 1 Times, 10 times for a course of treatment. The shortest treatment times 20 times, the longest 86 times. Results: All 8 patients in this group recovered consciously after the above treatment. Conclusions: Hyperbaric oxygen therapy has a significant effect on patients with persistent vegetative state. Treatment time longer than 40 times, should be phased, and should pay attention to strengthening nutrition supply.