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目的:探讨乳果糖在新生儿黄疸症临床治疗中的应用价值。方法:选取我院收治的新生儿黄疸症患儿103例,其中51例患儿仅采用蓝光治疗法进行临床治疗,作为对照组,剩下的52例患儿在对照组治疗的基础上,使用乳果糖进行辅助治疗,作为观察组。分别以两组患儿的治疗前后血清总胆红素水平、临床疗效、黄疸消退时间及并发症发生率作为临床观察指标,并使用SPSS 13.0软件包进行统计学分析。结果:观察组患儿治疗后的血清总胆红素水平明显低于对照组患儿,P<0.05;观察组患儿的临床疗效明显优于对照组患儿,P<0.01;观察组患儿的黄疸消退时间明显短于对照组患儿,P<0.05;两组患儿治疗过程中的不良反应发生率无显著性差异,P>0.05。结论:在蓝光治疗的基础上,使用乳果糖进行辅助治疗可有效的提高新生儿黄疸症的临床治疗效果,并缩短患儿黄疸的消退时间,且治疗过程中无不良并发症,具有临床推广应用价值。
Objective: To investigate the clinical value of lactulose in the treatment of neonatal jaundice. Methods: A total of 103 neonates with jaundice admitted to our hospital were enrolled. Among them, 51 children were treated with blue light therapy only. As the control group, the remaining 52 children were treated on the basis of the control group Lactulose adjuvant therapy, as the observation group. The serum total bilirubin level, clinical efficacy, jaundice remission time and the incidence of complications in two groups of children before and after treatment were taken as clinical observation indexes respectively and statistically analyzed by SPSS 13.0 software package. Results: The level of serum total bilirubin in the observation group was significantly lower than that in the control group (P <0.05). The clinical efficacy of the observation group was significantly better than that of the control group (P <0.01). The observation group Jaundice subsided time was significantly shorter than the control group, P <0.05; two groups of children with adverse reactions during the treatment there was no significant difference, P> 0.05. Conclusion: On the basis of blue light therapy, the adjuvant therapy with lactulose can effectively improve the therapeutic effect of neonatal jaundice and shorten the remission time of jaundice in children, and there are no adverse complications in the treatment, so it has clinical application value.