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有报道，在暴露于噪声后的大鼠血清和胃窦粘膜中发现锰－超氧化物歧化酶（Mn－SOD）的改变［１］；也有研究证实，铅可促使生物膜变性生成脂质过氧化物（LPO），进而使SOD活力降低。并且血铅含量与血中SOD活力及谷胱甘肽过氧化酶（GSH－Px）活力呈负相关，与LPO呈正相关［２］
It has been reported that manganese-superoxide dismutase (Mn-SOD) is found in rat serum and antral mucosa after exposure to noise [1]; studies have also shown that lead can degrade biofilm to produce lipid Oxide (LPO), thereby reducing SOD activity. And blood lead levels and serum SOD activity and glutathione peroxidase (GSH-Px) activity was negatively correlated with LPO was positively correlated [2]