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目的 :观察黄芪注射液和大剂量抗氧化剂维生素C(VC)、维生素E(VE)、丹参针联合治疗糖尿病肾病的疗效。方法 :对符合糖尿病肾病诊断标准的 60例患者随机分为治疗组 40例和对照组 2 0例 ,对照组给控制血糖、血压、限制蛋白质摄入量及对症治疗 ,治疗组在此基础上加用黄芪注射液和大剂量VC、VE、丹参针 ,4周为一疗程。结果 :治疗组总有效率为 82 5 % ,对照组总有效率为 5 0 %。两组相比较有较显著性差异 (P <0 0 1)。结论 :本组研究表明糖尿病肾病存在自由基代谢紊乱 ,应用黄芪注射液和大剂量抗氧化剂联合治疗对糖尿病肾病有非常显著性疗效。
Objective: To observe the curative effect of combination of Astragalus injection and high-dose antioxidants vitamin C (VC), vitamin E (VE) and salvia miltiorrhiza on diabetic nephropathy. Methods: Sixty patients who meet the diagnostic criteria of diabetic nephropathy were randomly divided into treatment group 40 cases and control group 20 cases, the control group to control blood sugar, blood pressure, limiting protein intake and symptomatic treatment, the treatment group on this basis With Astragalus injection and high-dose VC, VE, Salvia needle, 4 weeks for a course of treatment. Results: The total effective rate was 82.5% in the treatment group and 50% in the control group. There was a significant difference between the two groups (P <0.01). Conclusion: This study shows that there is free radical metabolism in diabetic nephropathy, the combination of Astragalus injection and high-dose anti-oxidant treatment of diabetic nephropathy have a very significant effect.