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亚急性坏死性淋巴结炎(Subacute nec-rotizing lymphadenitis,以下简称SNL)是最近几年才被认识的病因不明的非肿瘤性淋巴结肿大,属于淋巴结炎性免疫反应性疾病。临床上以长期的颈部淋巴结肿大、发热和白细胞减少为三大特征,病理组织学上见淋巴结内有广泛的凝固性坏死伴组织细胞反应性增强,但无中性粒细胞浸润为其特点。本病自1972年首先由日本东大第二外科藤本等在“内科”杂志上以颈部的恶急性坏死性淋巴结炎为题报告12例以来,受到日本病理和临床工作者们的广泛重视。到1983年为止,已有31例报告。在我国自1977年以来,仅有上海、
Subacute necrotizing lymphadenitis (hereinafter referred to as SNL) is an unknown etiologic lymphadenopathy of unknown etiology discovered in recent years and belongs to lymphoid inflammatory immunoreactive diseases. Clinically with long-term cervical lymph nodes, fever and leukopenia are the three major characteristics of the pathological histological lymph nodes have extensive coagulation necrosis with increased reactivity of cells, but no neutrophil infiltration as its characteristics . Since 1972, the disease was first reported by Japan’s Todai Second Surgical Fujimoto et al. In the journal Internal Medicine for the treatment of acute necrotic lymphadenitis in the neck. Twelve cases were reported by Japanese pathologists and clinicians. By 1983, 31 cases had been reported. In our country since 1977, only Shanghai,