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目的对男女类风湿关节炎患者血清性激素变化及临床意义进行分析探讨,为今后的临床诊治工作提供可靠的参考依据。方法抽取本院收治的临床确诊类风湿关节炎患者96例,另抽取同期健康体检者60例作为对照组,对这两组患者性激素水平检测,并对检测结果进行对比分析。结果女性患者PRL、E2水平均较对照组发生显著升高(P<0.05);男性患者FSH、LH水平与对照组存在明显差异(P<0.05)。结论男性与女性类风湿关节炎患者均存在明显的性激素水平变化,这对于临床诊治工作具有重要意义。
Objective To analyze the changes of serum sex hormones in patients with rheumatoid arthritis and to provide a reliable reference for future clinical diagnosis and treatment. Methods Ninety-six patients with clinically confirmed rheumatoid arthritis admitted to our hospital were enrolled in this study. Another 60 healthy subjects were selected as the control group. The levels of sex hormones in these two groups were tested and the results were compared. Results The levels of PRL and E2 in female patients were significantly higher than those in control group (P <0.05). The levels of FSH and LH in male patients were significantly different from those in control group (P <0.05). Conclusion There are obvious changes of sex hormone levels in both male and female patients with rheumatoid arthritis, which is of great significance for clinical diagnosis and treatment.