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目的调查首发或二次复发的缺血性卒中患者PSCI患病率及其影响因素。方法对2006-07～2010-05在郑州市中心医院神经内科门诊及病房就诊的患者采用横断面的研究方法,评估人口学因素、临床因素及脑血管病危险因素与PSCI的关系。结果共有791例纳入研究,PSCI的患病率为10.1%(80/791);不同卒中文化程度的患者PSCI的患病率不同,大学及以上者PSCI患病率最低,为2.5%;中学、小学、文盲卒中患者PSCI的患病危险分别是大学及以上组患者的3.51、6.63和6.05倍。非腔隙性脑梗死(P<0.01)、二次复发卒中(P<0.01)、抑郁状态(P<0.01)及ADL依赖(P<0.01)是PSCI的独立影响因素。结论在本组60岁以上的缺血性卒中人群中,PSCI的患病率为10.1%;文化程度、卒中发作次数、卒中类型、卒中后的抑郁状态及卒中后ADL状况是PSCI患病率的影响因素;高血压、糖尿病、心脏病等脑血管病的危险因素对PSCI的患病率无显著影响。
Objective To investigate the prevalence of PSCI and its influencing factors in patients with first-episode or second relapse of ischemic stroke. Methods From 2006-07 to 2010-05, a cross-sectional study was conducted in outpatients and ward visits of neurology department of Zhengzhou Central Hospital to evaluate the relationship between demographic factors, clinical factors and risk factors of cerebrovascular disease and PSCI. Results A total of 791 cases were enrolled in the study. The prevalence of PSCI was 10.1% (80/791). The prevalence of PSCI was different in patients with different education levels of stroke. The prevalence of PSCI in college and above was the lowest (2.5%). The prevalence of PSCI in primary and illiterate stroke patients was 3.51, 6.63 and 6.05 times higher than those in university and above patients respectively. Non-lacunar infarction (P <0.01), secondary recurrent stroke (P <0.01), depression (P <0.01) and ADL-dependent (P <0.01) were independent factors of PSCI. Conclusions The prevalence of PSCI is 10.1% in this group of 60-year-old ischemic stroke patients. The educational level, the number of strokes, the type of stroke, the post-stroke depression status and post-stroke ADL status are the prevalences of PSCI Influencing factors; risk factors of cerebrovascular diseases such as hypertension, diabetes and heart disease had no significant effect on the prevalence of PSCI.