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目的 比较18F 脱氧葡萄糖 (FDG)双探头符合线路SPECT(DHCI)与PET显像检测甲状腺癌转移病灶的价值。方法 2 6例甲状腺癌患者在同 1天分别进行了18F FDGPET和18F FDGDHCI显像 ,患者均已行甲状腺切除术和131I治疗。肿瘤转移病灶大小由计算机自动勾边在PET显像图中测定。结果 2 6例甲状腺癌患者中 ,18F FDGPET共发现 12 6个肿瘤转移病灶 ,其中18F FDGDHCI检测到 92个 (73 % ) ,CT发现 76个 (6 0 % ) ,18F FDGDHCI的病灶检测率明显高于CT(P <0 0 5 )。根据病灶部位分析 ,18F FDGDHCI与PET对转移病灶检测的符合率在头颈部为 6 8% ,胸部为 83% ,而在骨转移病灶的符合率仅为 5 2 % (P <0 0 1)。根据病灶大小分析 ,当肿瘤转移病灶大于 1 5cm时 ,18F FDGDHCI与PET结果的一致率达 98% ;而在 1～ 1 5cm的病灶检测中 ,18F FDGDHCI仅能发现 5 6 % ;当病灶小于 1cm时 ,18F FDGDHCI则难以发现 ,而PET发现的病灶最小直径为 0 7cm。结论 当肿瘤转移病灶的直径大于 1 5cm时 ,18F FDGDHCI与PET具有相似的诊断准确性。
Objective To compare the value of 18F deoxyglucose (FDG) dual-head coincidence line SPECT (DHCI) and PET imaging in the detection of metastatic thyroid cancer. Methods Twenty-six patients with thyroid cancer underwent 18F FDG PET and 18F FDG DC imaging on the same day, respectively. All patients underwent thyroidectomy and 131I treatment. The size of tumor metastasis was measured by PET computerized automatic crochet. Results Among 26 thyroid cancer patients, 12 6 tumor metastases were found in 18F FDG PETF, of which 92 (73%) were detected by 18F FDGDHCI, 76 (60%) were detected by CT, and the detection rate of 18F FDGDHCI was significantly higher On CT (P <0 05). According to the location of the lesion, the coincidence rate of 18F FDGDHCI and PET in detecting metastatic lesions was 68% in the head and neck and 83% in the chest, while the coincidence rate in the bone metastasis was only 52% (P <0.01) . According to the size of the lesion, when the tumor metastasis was larger than 15cm, the coincidence rate of 18F FDGDHCI and PET was 98%; while in the range of 1 ~ 15cm, 18F FDGDHCI only found 56%; when the lesion was less than 1cm , 18F FDGDHCI is difficult to find, and the smallest diameter of PET lesions found 0 7cm. Conclusions 18F FDGDHCI and PET have similar diagnostic accuracy when the diameter of tumor metastasis is greater than 15 cm.