论文部分内容阅读
目的:观察安替可胶囊结合化疗治疗晚期结肠癌的临床疗效。方法:经病理证实的晚期结肠腺癌初治患者:治疗组(42例)用化疗联合安替可胶囊治疗;对照组(40例)单纯给以化疗。化疗方案:FOLFOX4,每两周为1个周期,共6周期。观察两组临床疗效、白细胞的减少、镇痛及生活质量。结果:两组疗效有显著差异(P<0.05);化疗后对白细胞的影响两组无明显差异(P>0.05);两组治疗后疼痛均有不同程度的缓解,但治疗组明显高于对照组(P<0.05);治疗后两组的KPS评分均有提高,但治疗组较对照组明显(P<0.05)。结论:安替可胶囊配合化疗治疗晚期结肠癌有助于提高疗效,减轻疼痛,提高晚期结肠癌患者生活质量。
Objective: To observe the clinical effect of Antibiotic Capsule combined with chemotherapy in the treatment of advanced colon cancer. Methods: The patients with advanced colonic adenocarcinoma confirmed by pathology were treated with chemotherapy and Avastin in 42 cases. The control group (40 cases) was given chemotherapy alone. Chemotherapy program: FOLFOX4, every two weeks for a cycle, a total of 6 cycles. The clinical efficacy, reduction of leukocytes, analgesia and quality of life of the two groups were observed. Results: There was significant difference between the two groups (P <0.05). There was no significant difference between the two groups after chemotherapy (P> 0.05). After treatment, the pain relief of both groups was relieved to some extent, but the treatment group was significantly higher than the control group (P <0.05). After treatment, KPS scores of both groups increased, but the treatment group was significantly higher than the control group (P <0.05). Conclusion: Allitocel combined with chemotherapy for advanced colon cancer can help to improve curative effect, relieve pain and improve the quality of life of patients with advanced colon cancer.