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细菌耐药已成为当今一个全球性问题,越来越多的细菌出现耐药。近年来鼠伤寒沙门菌耐药已受到不少国家的关注。为此,我们在1997年10月至1998年12月的时间里,对本院门诊及住院儿童病人腹泻标本进行培养,分离出62株耐药鼠伤寒沙门菌,占总检出率的34.1％(62/182),这些菌株对复达欣、呋喃妥因、丁胺卡那霉素、头孢哌酮、头孢唑啉、庆大霉素及氨苄青霉素均耐药,并对本次分离的耐药菌株进行8组中药煎剂的药敏实验观察,以便找到治疗耐药鼠伤寒沙门菌的有效中药。1 材料1.1 菌株来源 标本菌株62株为1997年10月至1998年12月,来我院诊治的儿童腹泻标本分离获得,这些菌株对复达欣等11种抗生素均耐药。1.2 中药方剂 为本院中医科组方,具体方案是①号:板兰根10g、米壳6g、云苓6g;②号:败酱草10g、大白6
Bacterial resistance has become a global problem today, and more and more bacteria have developed resistance. In recent years, Salmonella typhimurium resistance has been concerned by many countries. To this end, we trained diarrhea specimens from our outpatient and inpatient children from October 1997 to December 1998. We isolated 62 strains of drug-resistant Salmonella typhi, which accounted for 34.1% of the total detection rate. (62/182), these strains were resistant to doxacin, nitrofurantoin, amikacin, cefoperazone, cefazolin, gentamicin, and ampicillin, and the isolates were resistant to this isolate. The susceptibility test of 8 groups of traditional Chinese medicine decoctions was performed to find an effective Chinese medicine for the treatment of resistant Salmonella typhimurium. 1 Materials 1.1 Strains Sources 62 strains of specimens were obtained from October 1997 to December 1998. The diarrhea specimens of children diagnosed and treated in our hospital were isolated. These strains were resistant to 11 antibiotics such as Fu Daxin. 1.2 Traditional Chinese medicine prescriptions are the prescriptions of the Institute of Traditional Chinese Medicine in this hospital. The specific plan is No. 1: Banlangen 10g, rice shell 6g, and Yunjing 6g; No. 2: Patrinia 10g, Dabai 6