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采用大鼠复制冷束缚应激性损伤模型，观察山莨菪碱、别嘌呤醇对应激性损伤的保护作用，结果显示两种药物均可减轻动物体内脂质过氧化反应及应激性胃损伤程度；说明微循环功能紊乱和氧自由基均与应激性损伤有关。
The rat model of cold-binding stress-induced injury was used to observe the protective effect of anisodamine and allopurinol against stress-induced injury. The results showed that both drugs can reduce lipid peroxidation and stress-induced gastric injury in animals ; Indicating that microcirculation dysfunction and oxygen free radicals are associated with stress injury.