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脊索瘤是一种少见的、具有侵袭性及局部破坏性的肿瘤。它可能起源于残留的原始脊索,可发生在沿骨骼中轴线上的任何部位,尤其多在骶尾区及颅底斜坡处生长。颅底脊索瘤因其位于重要功能区,治疗很棘手。作者通过长期的随访,认为手术切除肿瘤及术后质子-光子束放疗是治疗该病的最有效方法。基于该肿瘤的分类,选择经颅底入路手术切除脊索瘤,具有较低的死亡率和致残率。
Chordoma is a rare, invasive and locally destructive tumor. It may originate from the residual primitive chordate, which can occur anywhere along the axis of the skeleton, especially in the sacrococcygeal region and skull base slope. Skull base chordoma because it is located in the important functional areas, the treatment is very difficult. The author through long-term follow-up, that the surgical removal of the tumor and postoperative proton - photon beam radiotherapy is the most effective way to treat the disease. Based on the classification of the tumor, surgical resection of chordoma by transcranial approach is selected, with low mortality and morbidity.