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［目的］探讨卵巢原发性恶性淋巴瘤的诊断及鉴别诊断。［方法］用免疫组织化学及组织病理学方法观察３９例具有小圆形细胞为主要特征的卵巢恶性肿瘤。［结果］发现５例组织病理学特点、免疫组织化学标记符合卵巢原发性恶性淋巴瘤。［结论］卵巢原发性恶性淋巴瘤非常罕见、起病慢、症状不典型，临床及病理诊断较困难，单凭形态学方法很难与其它小圆形细胞肿瘤鉴别，免疫组织化学标记有一定价值。
[Objective] To investigate the diagnosis and differential diagnosis of primary ovarian malignant lymphoma. [Methods] 39 cases of ovarian malignant tumors with small round cells were observed by immunohistochemistry and histopathology. [Results] The histopathological features of 5 cases were found. The immunohistochemical markers were in line with the primary malignant ovarian lymphoma. [Conclusion] The ovarian primary malignant lymphoma is very rare, with a slow onset, atypical symptoms and difficult clinical and pathological diagnosis. It is very difficult to distinguish with other small round cell tumors by morphological methods. Immunohistochemistry has a certain value.