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目的分析并研究射频消融术对比手术切除治疗小肝癌的临床效果,研究临床Meta分析。方法采用计算机检索文献的方法,对中国万方数据库、中国知网数据库、中国超星数据库、中国维普数据库等数据库进行索引,搜集所有关于射频消融对比手术治疗小肝癌的文献,对所有文献的研究方法和研究质量进行评价,同时采用RevMan5.1版软件对其进行统计学分析。结果本研究最终纳入11个随机对照试验,通过Meta分析,结果表明两种治疗方法1年内的总生存率之间差异无统计学意义,1~3年无瘤生存率,1年复发率射频消融术组更多。手术以后对其并发症和总住院时间等进行比较,射频消融术比手术都更加优异,P<0.05。结论通过本研究的调查可以得出,射频消融术对于小肝癌来说,其短期内的治疗差异并不大,但从远期效果来看,采用手术切除治疗患者的生存率更高,复发率更低。
Objective To analyze and study the clinical effects of radiofrequency ablation in comparison with surgical resection of small hepatocellular carcinoma and to study the clinical meta-analysis. Methods A computer-based literature search method was used to index databases such as China Wanfang Database, CNKI Database, China Superstar Database and China Wipu Database, and to collect all the literature about radiofrequency ablation and contrast surgery for small hepatocellular carcinoma. And the quality of the research evaluation, and use RevMan5.1 version of the software for its statistical analysis. Results The study finally included 11 randomized controlled trials. Meta-analysis showed that there was no significant difference in the overall survival rate between the two treatment methods in 1 year, 1 to 3 years disease-free survival rate, 1-year recurrence rate of radiofrequency ablation More surgery group. Comparisons of complications and total length of stay after surgery were performed. Radiofrequency ablation was superior to surgery (P <0.05). Conclusion Through the investigation of this study we can conclude that radiofrequency ablation has little short-term treatment difference for small hepatocellular carcinoma, but in terms of long-term effect, the survival rate of patients treated with surgical resection is higher, and the recurrence rate Lower.