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本文研究了89例血液系统肿瘤性疾病患者的血清多胺含量。89例中,55例何杰金氏病,21例非何杰金氏病和13例急性粒细胞白血病。多胺检验应用以前介绍的酶的微量测定法。以25～35岁健康男性8例作对照。血标本在室温下凝固,用离心机移除各种血细胞而分离出血清。检测结果用 nMol/ml(毫微克分子/毫升)表示。急性粒细胞白血病患者的诊断系根据骨髓检查,何杰金氏病的诊断根据淋巴结活检和 Rye 分类法确定。他们或应用6个疗程的 COPP(环磷酰胺、长春新碱、强的松龙、甲基苄肼)化疗或用放疗。结果,对照组多胺范围为0.62～0.87nMol/ml,而全部89例癌症病例血清中
This article studied the serum polyamine levels in 89 patients with hematologic malignancies. Of the 89 patients, 55 had Hodgkin’s disease, 21 had non-Hodgkin’s disease and 13 had acute myeloid leukemia. Polyamine test using the previously described enzyme microtome assay. 8 to 35-year-old healthy male 8 as a control. Blood samples were allowed to solidify at room temperature, and various blood cells were removed by centrifuge to separate the serum. Test results are expressed as nMol / ml (nanograms per milliliter). The diagnosis of acute myeloid leukemia patients based on bone marrow examination, Hodgkin’s disease diagnosis based on lymph node biopsy and Rye classification. They either use 6 courses of COPP (cyclophosphamide, vincristine, prednisolone, procarbazine) chemotherapy or with radiotherapy. As a result, polyamines in the control group ranged from 0.62 to 0.87 nMol / ml, whereas all 89 cases of cancer serum