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对57例(男47例,女10例,年龄16～63岁)非髓系恶性肿瘤患者进行非净化自体外周血干细胞移植(APBSCT),分析PBSCT时CD34阈值与移植前化疗的关系。其中NHL29例,HD19例,骨髓瘤7例,其他2例。动员前31例接受一种化疗方案,26例接受两种不同的化疗方案,4例有TF4(毒性因子4,即BCNU,CCNU,氮介,马法兰)药物暴露史,6例接受扩大照射野的放疗,用Drake等的积分系统计算化疗药物积分。动员方案以Cy(55
Uncleaned autologous peripheral blood stem cell transplantation (APBSCT) was performed in 57 patients (47 males, 10 females, aged 16-63 years) with non-myeloid malignancy. The relationship between CD34 threshold and pre-transplant chemotherapy in PBSCT was analyzed. Of these, 29 were NHL, 19 were HD, 7 were myeloma, and 2 were other. Before mobilization, 31 patients received a chemotherapy regimen, 26 patients received two different chemotherapy regimens, 4 patients had TF4 (toxicity factor 4, ie, BCNU, CCNU, N-isoline, and melphalan) drug exposure history, and 6 patients received extended irradiation field. Radiotherapy, using the integral system of Drake et al. Mobilization Program with Cy (55)