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作者研究了21例慢性肾功能衰竭患者血尿酸与尿尿酸。男14例,女7例,年龄16~59岁。均无痛风、肥胖症、糖尿病、血液病。均予低蛋白(每日20~40g)和低嘌呤(每日10mg)膳食。慢性肾小球肾炎16例,慢性非结石性肾孟肾炎2例,肾淀粉样变化3例。患病1(1/2)~15年,氮质血症1~5年。肾功能均降低,肾小球滤过率降低至65.0~3.8ml/min。对照组为14名健康人,血尿酸4.87±0.24mg%,尿尿酸606±26.6mg/24h,尿酸清除率9.5±0.8ml/min。
The authors studied serum and uric acid levels in 21 patients with chronic renal failure. 14 males and 7 females, aged 16 to 59 years. No gout, obesity, diabetes, blood disease. Both low protein (daily 20 ~ 40g) and low purine (daily 10mg) diet. 16 cases of chronic glomerulonephritis, 2 cases of chronic non-calculous nephritis and 3 cases of renal amyloidosis. Disease 1 (1/2) ~ 15 years, azotemia 1 to 5 years. Renal function are reduced, glomerular filtration rate decreased to 65.0 ~ 3.8ml / min. The control group consisted of 14 healthy people with serum uric acid 4.87 ± 0.24mg%, uric acid 606 ± 26.6mg / 24h and uric acid clearance rate 9.5 ± 0.8ml / min.