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近三年来采用不同剂量与疗程吡喹酮治疗华支睾吸虫病248例,其中6～14岁儿童占81.5％。所用的疗法为12与14mg/kg,每日3次,连续五天(总剂量分别为180与210ms/kg),以及25mg/kg每日3次的二天疗法(总剂量为150mg/kg),治后3月用醛醚法检查,前者的粪便虫卵阴转率分别高达93.9％与100％;后者为97.7％,故25mg/kg每日3次的二天疗法为最适用的剂量与疗程。17例患者于治疗开始后收集48小时粪便淘虫,有13例排出成虫,3例排虫达百条以
In the past three years, 248 cases of clonorchiasis were treated with different doses and courses of praziquantel, in which 81.5% were children aged 6-14 years. Therapies used were 12 and 14 mg / kg three times a day for five consecutive days (total dose of 180 and 210 ms / kg respectively) and two days of 25 mg / kg three times daily for a total dose of 150 mg / kg, 3 months after treatment with aldehyde ether test, the former fecal insects egg negative conversion rates were as high as 93.9% and 100%; the latter 97.7%, so 25mg / kg three days a day for the two days of the most appropriate dose and treatment . Seventeen patients collected 48 hours of faecal noxious insects after the start of treatment, 13 of them excreted, and three of them ranked 100