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目的:探讨使用放大系统对睾丸精子行形态选择性卵细胞胞质内单精子注射术(ICSI)的临床结局。方法:回顾分析本中心2008年1月至2008年10月共66例无精子症患者行常规ICSI,2008年11月至2009年7月共39例无精子症患者用放大系统将睾丸精子放大6 000倍后,行卵细胞胞质内形态选择性单精子注射(IMSI)。结果:行ICSI的患者临床妊娠率为51.52%,种植率为30.67%,早期流产率为11.76%;行IMSI的患者临床妊娠率为56.41%,种植率为35.29%,早期流产率为4.50%。结论:无精子症患者的睾丸精子通过放大系统选择后行ICSI,早期流产率较常规ICSI有下降的趋势。
OBJECTIVE: To investigate the clinical outcome of intracytoplasmic sperm injection (ICSI) using morphological selective oocytes in testicular spermatozoa using an amplification system. Methods: A retrospective analysis of our center from January 2008 to October 2008 a total of 66 patients with azoospermia routine ICSI, November 2008 to July 2009 a total of 39 patients with azoospermia enlargement testicular sperm to enlarge 6 After 000-fold, intracytoplasmic morphogenetic single sperm injection (IMSI) was performed in oocyte. Results: The clinical pregnancy rate of ICSI patients was 51.52%, the implantation rate was 30.67%, the rate of early abortion was 11.76%. The clinical pregnancy rate was 56.41%, the implantation rate was 35.29% and the early abortion rate was 4.50%. CONCLUSION: Testis spermatozoa in patients with azoospermia choose ICSI through magnification system, and the rate of early miscarriage tends to decrease compared with conventional ICSI.