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近年来,我们早期应用大剂量纳络酮抢救急性重度中毒56例。现报告如下。 临床资料:56例患者中,男22例,女34例;年龄21～57岁,平均31岁。其中镇静药物中毒20例,酒精中毒14例,酒精中毒合并安定中毒8例,一氧化碳中毒4例,有机磷农药中毒10例。56例中,经皮肤、呼吸道吸收中毒4例,余均经口服中毒。中毒后至就诊时间15分钟至6小时,平均3小时。均有明确中毒病史。临床表现:56例均出现口唇紫红,深浅不同的昏迷。浅昏迷20例,中度昏迷26例,深昏迷10例,昏迷并发呼吸频率或节律改变42例,6例出现呼吸暂停;并发休克5
In recent years, we early use of large doses of naloxone rescue acute severe poisoning in 56 cases. The report is as follows. Clinical data: 56 patients, 22 males and 34 females; aged 21 to 57 years, mean 31 years. Among them, sedation drug poisoning in 20 cases, alcohol poisoning in 14 cases, alcohol poisoning combined with stability in 8 cases, carbon monoxide poisoning in 4 cases, organophosphorus pesticide poisoning in 10 cases. 56 cases, the skin, respiratory absorption poisoning in 4 cases, Yu were orally poisoned. After poisoning to treatment time 15 minutes to 6 hours, an average of 3 hours. Have a clear history of poisoning. Clinical manifestations: 56 cases appeared lips purple, different shades of coma. Shallow coma in 20 cases, moderate coma in 26 cases, 10 cases of deep coma, coma respiratory rate or rhythm changes in 42 cases, 6 cases of apnea; concurrent shock 5