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目的探讨米非司酮和甲氨喋呤联合治疗异位妊娠的效果。方法对32例停经在35～50d、血HCG<5000U/L、包块直径<3·2cm的异位妊娠患者,给予米非司酮和甲氨喋呤联合治疗,观察治疗成功率及输卵管通畅率。结果32例异位妊娠患者中仅3例保守治疗未成功,最终经手术治愈。其他29例全部治愈。成功率达到90%。29例患者在3个月后行输卵管通液检查完全畅通率达到100%。结论米非司酮和甲氨喋呤联合治疗异位妊娠成功率高,治疗后输卵管通畅率高,大大地提高了妇女将来的生育率。
Objective To investigate the effect of mifepristone and methotrexate in the treatment of ectopic pregnancy. Methods Thirty-two patients with ectopic pregnancy who had menopause at 35-50 days, blood HCG <5000 U / L and mass diameter <3.2 cm were treated with mifepristone and methotrexate. The success rate of treatment and tubal patency rate. Results 32 cases of ectopic pregnancy in only 3 cases of conservative treatment was unsuccessful, and ultimately cured by surgery. The other 29 cases were completely cured. Success rate of 90%. 29 patients in 3 months after tubal fluid check the complete flow rate of 100%. Conclusion The combination of mifepristone and methotrexate has a high success rate of ectopic pregnancy and high tubal patency rate after treatment, which greatly improves the future fertility rate of women.