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启东县是肝癌高发区,肝癌发病率一直在50/10万左右。近二年来,我所与北京、上海、江苏有关部门协作,进行了多方面的探索。一、乙型肝炎病毒感染:对启东肝癌病人进行了病因调查和分析;乙型肝炎病毒(HBV)感染和HBV感染标记物中HBsAg、抗—HBc IgG、抗—HBc IgM病例与对照组相比有极显著差异,相对危险性分别为25、6.4、11.33和4.4倍。肝癌病人HBV感染的流行率为91.1%,而对照组为48.2%(P<0.01)。启东肝癌与HBsAg关系10年前瞻性研究表明:80%以上肝癌病人血清中
Qidong County is a high incidence of liver cancer, the incidence of liver cancer has been around 50/10 million. In the past two years, we have conducted many exploration projects in collaboration with relevant departments in Beijing, Shanghai and Jiangsu. First, the hepatitis B virus infection: Qidong liver cancer patients were etiological investigation and analysis; hepatitis B virus (HBV) infection and HBV infection markers HBsAg, anti-HBc IgG, anti-HBc IgM cases compared with the control group There are very significant differences, the relative risks were 25,6.4,11.33 and 4.4 times. The prevalence of HBV infection in liver cancer patients was 91.1%, compared with 48.2% in the control group (P <0.01). Qidong liver cancer and HBsAg 10-year prospective study showed that: more than 80% of liver cancer patients serum