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目的:通过对205例癫痫患者SPECT脑血流显像与CT、MRI、EEG结果的对比分析,旨在评价SPECT脑血流显像在致痫灶定位诊断中的意义。方法:205例癫痫患者于发作间期进行了99mTc-ECDSPECT脑血流断层显像和EEG检查,其中103例和8l例同时进行了CT和MRI头颅扫描。结果:SPECT阳性检出率为74.l%,明显高于CT的55.3%和MRI的59.3%(P<0.005和P<0.025),但三者检出的病灶吻合较好。EEG的阳性率较高但定位欠准确。结果还显示致痫灶的分布以颞叶最多;在有产伤及脑外伤史儿童患者的阳性检出率明显高于其它病因的儿童患者(P<0.05),结论:SPECT脑血流显像在对癫痫病灶的定位诊断中具有较高的临床价值。
OBJECTIVE: To compare the results of SPECT cerebral blood flow imaging with those of CT, MRI and EEG in 205 epilepsy patients, and to evaluate the significance of SPECT cerebral blood flow imaging in the localization of focal eclampsia. Methods: Totally 205 patients with epilepsy underwent 99mTc-ECDSPECT CT and EEG examination in the interictal period. 103 and 81 patients underwent CT and MRI scans simultaneously. Results: The positive rate of SPECT was 74. l%, significantly higher than 55.3% of CT and 59.3% of MRI (P <0.005 and P <0.025), but the lesions detected by the three were well matched. The positive rate of EEG but less accurate positioning. The results also showed that the distribution of epileptogenic lesions in the temporal lobe most; children with traumatic injury and traumatic brain injury in the positive detection rate was significantly higher than other causes of children (P <0.05), Conclusion: Cerebral blood flow Imaging in the diagnosis of epilepsy lesions has a high clinical value.