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目的了解金华市本地人群与外来流动人口麻疹抗体水平,为制定和完善麻疹免疫策略提供科学依据。方法选取7个年龄组的630名本地人口和210名流动人口、180名18~25岁育龄期妇女、180名孕妇和90名8月龄以下儿童母亲,共1290人开展麻疹抗体水平监测,根据监测结果提出免疫策略。结果本地人群的麻疹抗体阳性率、保护率和几何平均浓度(GMC)分别为92.54%、78.73%和1774.19 mIU/ml;外来流动人口的麻疹抗体阳性率、保护率和几何平均浓度(GMC)分别为66.67%、40.95%和269.90 mIU/ml,本地人群的阳性率、保护率和GMC均明显高于外来流动人口(P<0.01)。育龄期妇女麻疹抗体阳性率、保护率和GMC分别为93.33%、62.78%和1194.13 mIU/ml;孕妇麻疹抗体阳性率、保护率和GMC分别为94.44%、65.56%和1298.82 mIU/ml;8月龄以下未患病儿童母亲的抗体GMC明显高于患病儿童母亲(P<0.05),4类特殊人群的疫苗接种率和接种意识均低于50%。结论金华市本地人群麻疹免疫水平较高,4类特殊人群的麻疹疫苗接种率、接种意识和免疫水平均不高。应加强常规免疫、强化免疫、应急接种、规范接种和健康教育等。
Objective To understand the level of measles antibody in local population and floating population in Jinhua City and provide scientific basis for formulating and improving measles immunization strategy. Methods A total of 630 local population, 210 floating population, 180 pregnant women aged 18-25 years, 180 pregnant women and 90 mothers of children under 8 months old from 7 age groups were enrolled in this study. A total of 1290 people were monitored for measles antibody levels. Monitoring results suggest immunization strategies. Results The positive rate, protective rate and geometric mean concentration (GMC) of measles antibody in local population were 92.54%, 78.73% and 1774.19 mIU / ml, respectively. The measles antibody positive rate, protective rate and geometric mean concentration (GMC) 66.67%, 40.95% and 269.90 mIU / ml respectively. The positive rate, protection rate and GMC of local population were significantly higher than that of migrant population (P <0.01). The positive rates of measles antibody, protective rate and GMC in women of childbearing age were 93.33%, 62.78% and 1194.13 mIU / ml, respectively. The positive rates of measles antibody, protective rate and GMC in pregnant women were 94.44%, 65.56% and 1298.82 mU / ml respectively. The GMC levels of mothers with unvaccinated children were significantly higher than those of affected mothers (P <0.05). The vaccination rates and vaccination awareness of the four special populations were less than 50%. Conclusion The level of measles immunity of local population in Jinhua City is high, and the vaccination rate, vaccination awareness and immunization level of the four special populations are not high. Should strengthen conventional immunization, intensive immunization, emergency vaccination, standardized vaccination and health education.