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本研究旨在通过对经冠脉造影证实的血管痉挛性心绞痛病人与冠脉造影完全正常的受试者的回顾性比较,检验冠脉痉挛的主要危险因素。方法:将经冠状动脉造影符合研究对象者351例,分成二组。第1组(血管痉挛组)175例(男165,女10),年龄33～76岁(平均55岁),均有胸痛,多为静息痛或夜间痛,极少数人只有劳累性胸痛。冠脉造影确诊为冠状动脉痉挛,但冠脉腔径狭窄<25%;第2组(对照组)176例(男110,女66),年龄34～81岁(平均56岁)。冠脉造影正常,麦角新碱诱发试验阴性。入选病人未用药前至少测3次血压,采用其均值。在病人禁食做冠脉造影时作血脂分析。
The aim of this study was to examine the major risk factors for coronary spasm by retrospective comparison of subjects with angiographically confirmed angiospastic angina and those with normal coronary angiography. Methods: 351 cases who were matched with coronary angiography were divided into two groups. Group 1 (vasospasm group) 175 (male 165, female 10), aged 33 to 76 years (mean 55 years), have chest pain, mostly rest pain or nocturnal pain, very few people with exertional chest pain. Coronary artery spasm was diagnosed by coronary angiography, but coronary artery stenosis was less than 25%. Group 2 (control group), 176 patients (male 110, female 66), aged 34 to 81 years (mean, 56 years). Coronary angiography was normal, ergometrine-induced test was negative. Selected patients without medication before measuring at least 3 times the blood pressure, using the mean. Blood lipids were analyzed when the patient was fasted for coronary angiography.