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金刚烷胺(Amantadine)1964年报告金刚烷胺在组织培养和小鼠体内可抑制某些正粘病毒和副粘病毒,其作用方式并未确定,似乎与干扰病毒脱壳有关。金刚烷胺的抗病毒活性已肯定,0.2~0.6μg/ml 可抑制大多数甲型流感病毒的复
Amantadine 1964 reports amantadine inhibits certain orthomyxoviruses and paramyxoviruses in tissue culture and in mice, and the mode of action is not established and appears to be related to interfering with virus dehulling. An amantadine antiviral activity has been affirmed, 0.2 ~ 0.6μg / ml can inhibit the majority of influenza A virus complex