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目的 探讨放射状角膜切开术 (RK)后不同时期切口破裂的临床表现、组织病理学改变和切口破裂的原因。方法收集 3例 RK后因钝挫伤发生切口严重破裂而摘除的眼球 ,10 0 g· L- 1 福尔马林液固定 ,石蜡包埋 ,切片 ,HE、甲氧胺蓝染色和光镜观察照像。结果3例眼球严重变形 ,眼内结构紊乱 ,视力丧失。 3例角膜浅层切口有上皮栓形成 ,前弹力层断裂错位 ;1例术后 2 9d的切口部分愈合部分缝隙存在 ;2例术后 2 a以上的切口瘢痕化 ,胶原纤维排列紊乱 ,深层切口有上皮岛 ;1例后弹力层断裂。结论 放射状角膜切开术降低了眼的张力强度 ,受钝挫后易发生眼球破裂 ,造成视功能严重受损
Objective To investigate the clinical manifestations, histopathological changes and causes of incision rupture at different stages after radial keratotomy (RK). Methods Three eyes of RK were enrolled in this study. The eyeballs were excised from severely incised wounds after blunt trauma. The specimens were fixed with 100 g · L -1 formalin, embedded in paraffin, sliced, stained with HE, . Results 3 cases of severe ocular deformity, ocular structure disorders, loss of vision. Three cases had epithelial thrombosis in the superficial corneal incision and dislocation of the anterior elastic layer. One case had part of the incision healing at 29 days after incision. Two cases had incision scarring and disorganization of collagenous fibers in 2 days after operation. Deep incision Epithelial island; 1 case after the elastic layer rupture. Conclusions Radial keratotomy reduces the ocular tension intensity and is prone to rupture of the eyeball after blunt trauma, resulting in severely impaired visual function