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目的 研究激光小梁成形术机理 ,进一步推广其在临床的应用。方法 对氩激光、倍频 Nd:YAG激光、半导体激光小梁成形术后 10 d、1m o、6 m o的猴眼房角进行组织学观察和比较。结果 激光小梁成形术后光凝区的小梁被破坏 ,前房侧小梁表面出现一从角膜内皮细胞延伸过来的细胞层。三种波长激光都能有效地进行小梁成形术 ,其中半导体激光所造成的损伤较其他 2种大。结论 房水流出阻力下降 ,房水流出量的增加可能与光凝区前房侧小梁网表面的细胞层和非光凝区小梁间隙增大、Schlem m管扩张有关。
Objective To study the mechanism of laser trabeculoplasty to further promote its clinical application. Methods Histological observation and comparison were made on the 10 days, 1 mm and 6 mm ophthalmic angle after argon laser, double frequency Nd: YAG laser and laser trabeculoplasty. Results The trabeculae in the photocoagulation area after laser trabeculation were destroyed, and a cell layer extending from the corneal endothelial cells appeared on the surface of the anterior chamber trabeculae. Three kinds of wavelength laser can effectively trabecular angioplasty, in which the semiconductor laser damage caused than the other two. Conclusions The decrease of aqueous outflow resistance and the increase of aqueous outflow may be related to the increase of the interstitial spaces between the cell layer and the non-photocoagulation area on the surface of the anterior chamber trabeculae in photocoagulation and the expansion of Schlemm’s canal.