论文部分内容阅读
目的探讨连云港市病毒性脑膜炎暴发的流行特征及其影响因素。方法采样统一的流行病学调查表对病例进行调查,收集2004年以来全市各县区病毒性脑膜炎住院病例资料,进行流行病学及临床资料分析;采用1∶2配比病例对照研究的方法分析流行因素;23份脑脊液标本送江苏省疾病预防控制中心检测,并进行病毒分离。结果2004-2005年全市各县区病毒性脑膜炎病例呈现散发状态;2006年1～7月份共查出病例数为968例,从6月份起出现疫情上升,1县2区出现暴发,7月份达高峰,暴发病例为473例,占全市总病例数的48.86%;主要累及15岁以下儿童,占94.44%;男性多于女性,男女比为2.65∶1;主要临床症状体征为发热、头痛、呕吐、脑膜刺激征阳性、脑脊液有核细胞增多。饭前洗手与多吃瓜果为保护因素,说明该病与不良卫生习惯有关系。23份脑脊液经PCR检测,16份Echo30肠道病毒阳性,并进行病毒分离。结论2006年夏季江苏省连云港市病毒性脑膜炎出现一次暴发并波及1县2区,致病病原体为Echo30肠道病毒,不良卫生习惯可能是导致该病发生流行的危险因素。
Objective To investigate the epidemiological characteristics of viral meningitis outbreak in Lianyungang and its influencing factors. Methods Sampling a unified epidemiological questionnaire to investigate the cases collected from all counties in the county since 2004, viral meningitis inpatient data, epidemiological and clinical data analysis; using 1: 2 ratio of case-control study Analysis of epidemic factors; 23 samples of cerebrospinal fluid were sent to Jiangsu Provincial Center for Disease Control and Prevention for detection, and virus isolation. Results From 2004 to 2005, the cases of viral meningitis in all districts and counties in the city were exuded. From January to July 2006, the number of cases was 968 cases. The epidemic increased from June, and the outbreak occurred in 2 districts of 1 county. In July, Accounting for 48.86% of the total number of cases in the city; mainly involving children under 15 years old, accounting for 94.44%; men more than women, the male to female ratio was 2.65: 1; the main clinical symptoms and signs were fever, headache, Vomiting, positive meningeal sign, cerebrospinal fluid nucleated cells increased. Wash hands before meals and eat fruits as a protective factor, indicating that the disease and poor health habits are related. 23 cerebrospinal fluid was detected by PCR, 16 Echo30 enterovirus positive, and virus isolation. Conclusions In summer of 2006, an outbreak of viral meningitis in Lianyungang City, Jiangsu Province affected one district and two districts. The pathogenic agent was Echo30 enterovirus. Adverse health habits may be the risk factors for the epidemic.