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目的探讨人类免疫缺陷病毒(HIV)感染者中乙型肝炎病毒(HBV)的混合感染状况以及对HBV的免疫水平。方法对59份HIV-1抗体阳性血清,采用酶联免疫吸附试验(ELISA)检测HBV表面抗原(HBsAg)和表面抗体(HBsAb)。分析HIV感染者中HBV感染及免疫情况。结果HIV/HBV混合感染率为13.56%(8/59),HBsAb阳性率为55.93%(33/59),不同性别、年龄、感染途径的HIV/HBV混合感染率以及HBsAb阳出率,各组之间分别比较,均无显著性差别。结论HIV/HBV混合感染率相对较低,HBsAb的阳性率较高,这与人群自然免疫、人工免疫有关,在HIV感染者中接种乙型肝炎疫苗对于预防HBV的感染具有重要意义。
Objective To investigate the combined infection status of hepatitis B virus (HBV) and immunization against HBV in human immunodeficiency virus (HIV) infected patients. Methods Fifty-nine HIV-1 positive sera were tested for serum HBsAg and HBsAb by enzyme-linked immunosorbent assay (ELISA). Analysis of HBV infection and immune status in HIV-infected persons. Results The prevalence of HIV / HBV was 13.56% (8/59), the positive rate of HBsAb was 55.93% (33/59). The prevalence of HIV / HBV infection and HBsAb positive rate in different sexes, ages and routes of infection were higher in each group Respectively, no significant difference between. Conclusion The mixed infection rate of HIV / HBV is relatively low, and the positive rate of HBsAb is high, which is related to the natural immunity and artificial immunity of the population. Vaccination of hepatitis B vaccine among HIV-infected persons is of great significance for preventing HBV infection.