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目的分析多普勒组织成像(DTI)对糖尿病(DM)患者早期左心室功能异常的评估价值。方法选取2013年6月—2014年6月在江苏省如皋市人民医院超声科进行检查的DM患者40例作为研究组,同期体检健康者35例作为对照组。两组患者均采用常规超声检查检测左心室舒张早、晚期最大血流速度(E值、A值);采用改良Simpson法检测左心室射血分数(LVEF)、左心室收缩末期容积(LESV)、左心室舒张末期容积(LEDV);采用DTI检查检测瓣环左心室收缩期峰值速度(Sa)、局部等容收缩时间(ICT)、局部射血时间(ET)及左心室舒张早、晚期运动峰值(Em、Am)。结果两组患者LESV、LEDV、LVEF比较,差异均无统计学意义(P>0.05);研究组患者E值低于对照组、A值高于对照组(P<0.05)。两组患者前壁、后壁、侧壁、后室间隔Sa及各部位ICT比较,差异均无统计学意义(P>0.05);研究组患者下壁和前室间隔Sa均低于对照组,各部位ET均高于对照组(P<0.05);研究组患者Em低于对照组,Am高于对照组(P<0.05)。结论 DTI能够较敏感、可靠地检测出DM患者早期心肌运动异常,可作为评价DM患者早期左心室舒张、收缩功能异常的检查手段。
Objective To evaluate the value of Doppler tissue imaging (DTI) in evaluating early left ventricular dysfunction in patients with diabetes mellitus (DM). Methods From June 2013 to June 2014, 40 patients with DM in the Department of Ultrasound of Rugao People’s Hospital of Jiangsu Province were selected as the study group, and 35 healthy people in the same period were selected as the control group. In both groups, the maximal blood flow velocity (E value and A value) of early and late diastole of left ventricle were measured by routine ultrasonography. Left ventricular ejection fraction (LVEF), left ventricular end-systolic volume (LVEF) Left ventricular end-diastolic volume (LEDV). The left ventricular systolic peak velocity (Sa), local isovolumic systolic time (ICT), local ejection time (ET) and left ventricular diastolic early and late peak exercise (Em, Am). Results There was no significant difference in LESV, LEDV and LVEF between the two groups (P> 0.05). The E value of the study group was lower than that of the control group, and the value of A was higher than that of the control group (P <0.05). The anterior wall, posterior wall, side wall, posterior interventricular septum Sa and ICT in different groups showed no significant difference between the two groups (P> 0.05). In the study group, the subspace Sa and anterior septum were lower than the control group, The ET in each group was higher than that in the control group (P <0.05). Em in the study group was lower than that in the control group, and Am was higher than that in the control group (P <0.05). Conclusions DTI can detect early myocardial abnormalities in DM patients more sensitively and reliably, and can be used as a test to evaluate the early left ventricular diastolic and systolic dysfunction in patients with DM.